Annual Report on External Quality Assessment of Biochemical Genetics in Korea (2013) / 임상검사와정도관리
Journal of Laboratory Medicine and Quality Assurance
;
: 64-70, 2014.
Article
in Korean
| WPRIM
| ID: wpr-65817
ABSTRACT
Two trials of external quality assessment (EQA) of conventional newborn screening tests for phenylketonuria, galactosaemia, congenital adrenal hyperplasia, maple syrup urine disease, homocystinuria, and congenital hypothyroidism, as well as of newborn screening tests using tandem mass spectrometry were performed in 2013. A total of 32 specimens in the form of dried blood spots were distributed to 16 laboratories and the response rate of these laboratories was 100%. Total T4, free T4, 17-hydroxyprogesterone, leucine, isoleucine, galactose, methionine, alanine, C8/C2, C8/C10, and C5-OH did not meet the accepted performance criteria. The mean, standard deviation, coefficient of variation, median, and cut-offs were evaluated for each analyte in the newborn screening tests. Two trials of EQA for the analyses of methylmalonic acid, vanillylmandelic acid, very long fatty acids, organic acids, and amino acids were also performed. A well-designed EQA program and continuous education would improve the performance of biochemical genetic tests.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenylketonurias
/
Vanilmandelic Acid
/
Mass Screening
/
Adrenal Hyperplasia, Congenital
/
17-alpha-Hydroxyprogesterone
/
Congenital Hypothyroidism
/
Alanine
/
Education
/
Tandem Mass Spectrometry
/
Fatty Acids
Type of study:
Screening study
Limits:
Humans
/
Infant, Newborn
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of Laboratory Medicine and Quality Assurance
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS