Progress of microRNA-29b in tumors / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 707-710, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-658219
ABSTRACT
MicroRNA (miRNA) is a kind of highly conserved microRNA molecules that regulate gene expression after transcriptional levels in eukaryotes. Numerous evidences indicate that miRNA can regulate malignant phenotypes of neoplasms by repressing the expressions of critical oncogenes or tumor suppressor genes, and abnormal expression of miRNA becomes one of the most important features of cancer. The expression of miR-29b was low in multiple types of tumors and its up-regulated expression will depress the expression of some target genes, which plays a crucial role in the occurrence and development of various neoplasms and is expected to serve as a biomarker for early diagnosis and prognosis assessment becoming a novel target of drug development and new treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Screening study
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2017
Type:
Article
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