Regional homogeneity of brain in irritable bowel syndrome patient:a resting state fMRI study / 实用医学杂志

ABSTRACT

Objective To investigate regional homogeneity(ReHo)of brain in patients with irritable bowel syndrome(IBS)using resting-state functional MRI(rs-fMRI). Methods 23 patients with IBS and 23 age-,edu-cation-,and sex-matched normal healthy subjects(control group)were collected in our hospital from July 2015 to June 2016. All of them underwent rs-fMRI. The rs-fMRI data were analyzed with the regional homogeneity method. Results As compared with the control group ,the IBS group showed significantly increased ReHo values in the left occipital lobe,and decreased ReHo values in the right insular,the right superior temporal gyrus and bilateral middle frontal gyrus(P < 0.001). Conclusion One or more brains of the IBS patients showed significant differ-ences in the spontaneous neuronal activity compared with healthy controls.