Lizhong Fuyuan Decoction combined with acupuncture treats chronic atrophic gastritis with spleen deficiency and phlegm stasis / 中成药

ABSTRACT

AIM To observe the therapeutic effects of Lizhong Fuyuan Decoction (LFD) (Astragali Radix,Atractylodis macrocephalae Rhizoma,Poria,etc.) combined with acupuncture (Weishu,Zhongwan,Neiguan and Zusanli) on chronic atrophic gastritis with spleen deficiency and phlegm stasis by randomized,parallel controlled trial.METHODS One hundred and eight patients were randomly and equally divided into LFD + acupuncture group,LFD group and control group (folic acid),four months as a course of the treatment.The main clinical symptoms and signs in the three groups before and after the treatment were observed,and the gastroscopic analysis and physico-chemical examination were compared.RESULTS There were significant differences in color and activity of gastric mucosa in each group,and there was also significant difference in TCM symptom score before and after the treatment.In terms of symptom curative effect,there was significant difference among various groups.No significant differences among various groups were observed in pathological efficacy,immunohistochemistry and comprehensive curative effect.The total effective rate of the LFD + acupuncture group reached 42％,that of the LFD group was 36.5％,and that of the control group obtained 24.1％.Analysis of variance (ANOVA) and rank sum test indicated that the differences between the two groups were statistically significant.CONCLUSION LFD combined with acupuncture can optimize the curative effects on chronic atrophic gastritis with spleen deficiency and phlegm stasis.