Effects of Placenta Granules on outcome of mild stimulation protocol / 中成药

ABSTRACT

AIM To observe the effects of Placenta Granules (Hominis placenta) on endometrial receptivity and embryo outcome.METHODS Ninety infertile patients meeting the kidney Qi deficiency syndrome were randomly divided into H.placenta group (treatment group) and control group.The endometrial thickness,endometrial morphology,blood flow,ovum pick-up number,fertilization number,developmental embryo number,highquality embryo number,pregnancy rate,implantation rate and abnormal pregnancy rate were observed in the two groups.RESULTS There were significant differences in blood flow,numbers of developmental embryo and high-quality embryo (P ＜ 0.05).Ten cases in the control group and fourteen cases in the treatment group reached standard for fresh embryo transplantation.The number of HCG positive in the control group was four cases,which was lower than six cases in the treatment group.There were three cases in the control group on number of clinical pregnancy,and six cases in the treatment group.There were four cases in the control group on implantation rate,and nine cases in the treatment group.All the differences were not statistically significant (P ＞ 0.05).CONCLUSION Placenta Granules can improve the endometrial receptivity and high-quality embryo number in ovarian-stimulation stage under mild stimulation protocol,showing a rising trend in clinical pregnancy rate.