Research and clinical application advances in the pharmacogenomics of warfarin / 中国医师进修杂志
Chinese Journal of Postgraduates of Medicine
; (36): 950-954, 2017.
Article
in Zh
| WPRIM
| ID: wpr-658947
Responsible library:
WPRO
ABSTRACT
Warfarin is widely used as an oral anticoagulant in clinic in China. It has narrow therapeutic index, large individual differences on dosage and the variability in warfarin dosage depends on many factors, including gene polymorphism, age, diet habits and so on. For clinicians, how to optimize the individual therapeutic regimen of warfarin is becoming a significant part of their work. In recent years, studies on genetic pharmacogenomics of warfarin are reported frequently. It is found that multiple gene polymorphisms can affect the efficacy of warfarin. We will introduce the gene polymorphism of some warfarin related genes and their effects on warfarin, and the advances of warfarin individual therapeutic regimen will also be discussed here.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Postgraduates of Medicine
Year:
2017
Type:
Article