Study on the Extraction Technology of Compound Radix Fici Hirta Granule / 中国药房
China Pharmacy
;
(12): 3976-3979, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-659250
ABSTRACT
OBJECTIVE:
To optimize the extraction technology of Compound radix fici hirta granule.METHODS:
Using the transfer rate of psoralen and amygdalin in extraction liquid of Compound radix fici hirta granule and extraction rate as indexes, U12(6×4×3)uniform design was used for the test,the effects of amount of adding water,extraction time,extraction times on the extraction technology were investigated,and optimized technology was verified by three pilot scale tests.RESULTS:
The optimal technology was as follow as 10-fold water,extracting for 3 times,60 min each time. Under the conditions,transfer rate of pso-ralen and amygdalin and extraction rate were 82.51%(RSD=1.45%,n=3),93.69%(RSD=0.85%,n=3),18.89%(RSD=0.74%,n=3),respectively. The validated results were in the 95% confidence interval of predictive value.CONCLUSIONS:
The optimized extraction technology is stable and feasible,and provides the scientific basis for the follow-up development of the prepa-ration.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2017
Type:
Article
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