Clinical analysis of carboprost tromethamine injection and misoprostol in prevention of postpartum hemorrhage / 中国生化药物杂志

ABSTRACT

Objective To investigate the clinical efficacy of carboprost tromethamine injection and misoprostol in high-risk of maternal postpartum. Methods 60 maternal with high-risk postpartum hemorrhage from January 2012 to January 2017 were divided into the control group and study group,30 case in each group.The two groups were treated with cesarean section surgery, the control group received misoprostol sublingual, study group were treated with carboprost tromethamine injection by intramuscular injection, recorded two groups of postpartum hemorrhage andthe incidence of adverse reactions. Results The study group of 2h postpartum hemorrhage, 24 h postpartum hemorrhage were significantly lower than control group (P<0.05); the incidence of adverse drug reactions in study group was 10.00%, and control group was 13.33%, there is no significant difference. Conclusion Carboprost tromethamine injection was effective and safe in the prevention of postpartum hemorrhage, which was beneficial to the quality of life and safety of high-risk postpartum women.