Comparative observation on the effect of interventional therapy and drug therapy on the treatment of the patients with cerebral infarction and the influence on coagulation function / 中国生化药物杂志

ABSTRACT

Objective To investigate the clinical effect of interventional therapy and drug therapy on the treatment of the patients with cerebral infarction and the influence on coagulation function. Methods A total of 92 patients with cerebral infarction from April 2016 and June 2017 were randomly divided into the study group (n=46) and the control group (n=46) by single and double digit method. The study group were treated with interventional therapy, and the control group were treated with drug conservative treatment. The effect and coagulation function in the two groups were recorded and compared. Results After treatment, NIHSS scale scores in the two groups were decreased significantly than before (P<0.05), the difference between the two groups has no statistically significant; There were no significant changes in the levels of APTT, PT and FIB before and after treatment in the study group. Compared with pre-treatment, there were significant changes in the levels of APTT, PT, FIB in the control group (P<0.05). Conclusion Clinicians should select the appropriate treatment program according to the actual situation of patients, so as to ensure the effectiveness and safety of the patients with cerebral infarction.