Advances in research on microglia associated with schizophrenia / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 1105-1107, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-660210
ABSTRACT
Microglia plays multiple roles in the pathophysiology of schizophrenia .Activated microglia can induce a cascade of immune responses leading to neuroimmunological abnormalities , including the release of proinflammatory cytokines , the metabolic ab-normalities of the kynurenic acid pathway , and the oxidative stress response .On the other hand , it can lead to the neurodevelopmental abnormalities through the abnormal pruning of synapses and reducing the lack of neurotrophic support , eventually having psychotic symptoms.This article reviews the recent advances in the pathogenesis of microglia being involved in schizophrenia .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2017
Type:
Article
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