Effect and mechanism of extracorporeal shock wave therapy on patients with type ⅢB chronic prostatitis(CP/CPPS) / 实用医学杂志

ABSTRACT

Objective To investigate the effect and mechanism of extracorporeal shock wave therapy(ES-WT)on typeⅢB chronic prostatitis. Methods A total of 90 patients with CP/CPPS in our department from June 2015 to February 2017 were collected and randomly divided into experimental and control groups ,each with 45 cases. The control group was treated with hyperthermia. The experimental group was treated with ESWT. Both two groups were treated for 2 courses. Following parameters were collected after two groups were treated for 2 courseschronic prostatitis symptom score (NIH-CPSI),the International Prostate Symptom Score (IPSS),the content changes in prostate fluid IL-8,TNF-alpha,IL-1 beta,lecithin and the content change of urine IL-8,TNF-alpha, IL-6. Results After 2 courses of treatment,compared with the control group,the overall efficiency of experimen-tal group was increased(91.11%vs. 66.67%,P<0.05). NIH-CPSI(13.12 ± 1.71 vs. 18.16 ± 1.33,P<0.05)and IPSS(8.03 ± 1.78 vs. 13.04 ± 1.89,P<0.05)scores were decreased. In terms of inflammatory,compared with the control group,in the experimental group,the content of lecithin body was significantly increased. The levels of inflammatory factors IL-8、TNF-α、IL-1βwere significantly decreased in the prostatic fluid and urine. Conclusion ESWT is safe and effective in the treatment of type ⅢB prostatitis ,which may be caused by reducing the local inflammatory response in the prostate.