Integrative Psycho-gastrointestinal Thinking and Strategies in the Practice of Management of Inflammatory Bowel Disease / 胃肠病学

ABSTRACT

Treatment for inflammatory bowel disease (IBD)is becoming a great challenge in clinical practice. Currently,treatment strategies are focused on attenuation of intestinal inflammation and autoimmune reactivity as well as surgical therapy. However,these measures cannot prevent the progression of pathophysiological process in quite a number of patients. The understanding of brain-gut interaction in the pathogenesis of IBD has shed light on the treatment of this disease. This review article discussed the importance of integrative psycho-gastrointestinal thinking and strategies targeting on the intestinal inflammation-associated psychological factors,neuroimmune abnormalities,and intestinal microbiota in the management of IBD in clinical practice.