Clinical application of serum follicular statin 1 in the diagnosis of chronic heart failure / 国际检验医学杂志

ABSTRACT

Objective To study the application value of serum follicular statin 1(FSTL-1) in the diagnosis of chronic heart fail-ure(CHF) .Methods A total of 60 CHF children treated from January 2013 to January 2016 in hospital were selected as observa-tion group .According to New York Heart Association (HYHA) ,the subjects were divided into Type Ⅱ group ,Type Ⅲ group and Type Ⅳ group ,20 cases in each group .In addition ,60 healthy children were selected as control group .FSTL-1 ,NT-proBNP and LVMI were detected and analyzed .Results FSTL-1 ,NT-proBNP and LVMI in Type Ⅱ group ,Type Ⅲ group and Type Ⅳ group were higher than those of control group(P< 0 .05) .As the grade of cardiac function increasing ,FSTL-1 ,NT-proBNP and LVMI were higher(P<0 .05) .FSTL-1 had positive correlations with NT-proBNP and LVMI .The positive rate of FSTL-1 for diagnosis CHF was 96 .67% ,which had no significant difference with gold standard (P>0 .05) .Conclusion With the progress of illness ,the level of FSTL-1 increases ,which is importance in the diagnosis and monitoring of CHF .It is worthy of further application and pro-motion in clinical practices .