Clinical contrast study of Weikangling and Weifuchun for chronic atrophic gastritis and precancerous lesions / 药物评价研究

ABSTRACT

Objective To explore the clinical effect of Weikangling and Weifuchun treatment of chronic atrophic gastritis and precancerous lesions.Methods 85 cases of CAG precancerous lesions treated in our hospital from Jan.2012 to Dec.2016 were selected as the research object,and were randomly divided into control group (n =41) and study group (n =44).The control group were given Weifuchun,and the study group were given Wei Kangling.The pathological score and clinical efficacy were compared between the two groups before and after treatment.Results After treatment,inflammation,atrophy,intestinal metaplasia scores of the two groups were significantly decreased than before treatment in addition to dysplasia (P ＜ 0.05),and inflammation and intestinal metaplasia in the study group were significantly lower than those in the control group (P ＜ 0.05).The total effective rate of the study group was 90.91％,which was higher than75.61％ of the control group (P ＜ 0.05).Conclusions The effect of Wei Kangling in treating precancerous lesions of CAG is significant,especially for the histological changes of inflammation and intestinal metaplasia.