Pretreatment diagnosis and surgical management of minimally invasive adenocarcinoma / 中华胸心血管外科杂志

ABSTRACT

Objective In 2011's new IASLC-ATS-ERS(International Association for the Study of Lung Cancer,American Thoracic Society,and European Respiratory Society) lung adenocarcinoma classification,adenocarcinoma in situ and minimally invasive adenocarcinoma(MIA) substituted for bronchioloalveolar carcinoma.The excellent prognosis wins these two histologic types a lot of attention.With the development of image technology,more and more lung adenocarcinomas are detected in early stage.Tumors showing a ground-glass nature in preoperative CT scans are more likely to be minimally invasive adenocarcinoma.This review discusses from the following 6 aspects.Imaging characteristics of MIA,the diagnostic value of intraoperative frozen section,preoperative localization,selection of surgical approaches for ground-glass opacity(GGO) nodules,the extent of lymph nodes dissection and management of multiple primary lung adenocarcinoma.The clinical guideline for early-stage lung adenocarcinoma is still controversial,strong evidence and further studies are needed.