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Preoperative prediction of the nature of gallbladder polypoid / 中华普通外科杂志
Chinese Journal of General Surgery ; (12): 956-961, 2017.
Article in Chinese | WPRIM | ID: wpr-663154
ABSTRACT
Objective To evaluate the risk factors of gallbladder neoplastic polyps and establish a Logistic regression equation.Methods We retrospectively collected clinicopathological data of 580 patients who underwent cholecystectomy for gallbladder polyps.Compared to the clinicopathological parameters between non-neoplastic polys and neoplastic polys,and adenomas and gallbladder cancer by univariate and multivariate analysis,we developed a Logistic regression equations to conduct diagnostic test.Results The univariate analyses showed that ultrasonic measuring gallbladder basal > 0.72 cm,CEA > 1.51 ng/ml,CA199 > 12.92 U/ml for the diagnosis of gallbladder adenomatous polyps were statistically significant respectively (P < 0.05).Multivariate regression analysis showed regression equations 1.When P > 0.256,the sensitivity of the diagnosis of adenomatous polyps was 72.4%,the specificity was 80.0%,and the whole correct ratio was 77.8%.The positive likelihood ratio of adenomatous polyps was 10.44,AUC was 0.828.As for neoplasm risk factors,the CT value > 32.50 Hu for the diagnosis of malignancy was statistically significant (P < 0.05).Multivariate regression analysis displayed regression equations 2.When P > 0.496,the sensitivity for the diagnosis of adenomatous polyps was 86.0%,the specificity was 90.5%,and the whole correct ratio was 89.0%.The positive likelihood ratio for malignant tumor was 9.08,AUC was 0.938.Conclusion Preoperatively,patients' age,symptoms,ultrasonic parameters,can be used to develop a regression equation to predict accurately the nature of gallbladder polyps.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of General Surgery Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of General Surgery Year: 2017 Type: Article