Detection rate of colorectal adenoma and its risk factors in different areas / 中国肿瘤临床

ABSTRACT

Objective:To compare the detection rate of colorectal adenoma (CRA) and its risk factors in different areas. Methods:Pa-tients with CRA from the 7th People's Hospital of Chongqing were designated to area group A (n=2182), and those from the 281 Hospi-tal of PLA in Qinhuangdao were designated to area group B (n=1866). The high risk group was screened on the basis of the following factors①positive fecal occult blood;②colorectal cancer history of first-degree relatives;③intestinal adenoma history;④can-cer history;⑤change in defecation habit;and⑥history of at least two of the followingchronic diarrhea, chronic constipation, mu-cus and bloody stool, chronic appendicitis or appendix removal, and chronic cholecystitis or gallbladder removal. The detection rate of CRA and the high risk groups, the distribution of risk factors, and the detection rate of CRA in every risk factor in the two groups were compared. Results:The detection rate of CRA (15.6%) and the high risk group (25.8%) in area group A were similar to those in area group B (15.2%, 25.4%) (P>0.05). The distributions of risk factors from high to low in the two groups were⑤,⑥,①,③,②, and④. The distribution of risk factor⑤was higher in area group A (36.4%) than in area group B (30.6%) (χ2=3.900, P=0.048). The detec-tion rate of CRA in area group A (57.6%) with factor⑤was higher than that in area group B (44.1%) (χ2=6.131, P=0.013). Conclusion:The detection rate of CRA and the high risk group in the 7th People's Hospital of Chongqing were similar to those in the 281 Hospital of PLA. By contrast, the distributions of risk factors differ in the two area groups. Therefore, the screening direction of CRA in different areas should be based on the risk factors.