A study on the knee joint function recovery and the quality of life by the massage and manipulation combined external application of Chinese medicine for the patients after knee arthroscope surgery of osteoarthritis / 国际中医中药杂志

ABSTRACT

Objectives In order to evaluate the difference of the clinical effect of the knee joint function recovery and the quality of life by the massage and manipulation combined external application of Chinese medicine for the patients after knee arthroscope surgery of osteoarthritis. Methods A total of 160 hospitalized patients after knee joint arthroscope surgery of osteoarthritis from Tongchuan People's Hospital, Shanxi Tongchuan, were randomly divided into manipulation treatment group and control group. The manipulation treatment group revieved the manipulation combined with external application of Chinese medicineafter arthroscope surgery, and the control group received the regular massage combined with external application of Chinese medicine. Both groups were treated for two weeks. The WOMAC scale, ISOA scale and KPS rating scale were evaluated before and after treatment.The joint fluid IL-1β, TNF-α, the content of NO were detected before and after treatment of 3 months.Results After treatment,the WOMAC(21.26 ±13.16 vs.31.19 ± 12.67, t=8.967), ISOA (3.28 ± 1.52 vs. 6.45 ± 2.31, t=5.261) of the manipulation group were significantly lower than those of the control group(P<0.05);the KPS(88.26 ±7.42 vs.76.39 ±8.59,t=6.164)of the manipulation group was significantly higher than the control group (P<0.05); the TNF-α (21.31 ± 10.43 ng/ml vs. 28.29 ± 11.74 ng/ml, t=6.219), IL-1β (11.36 ± 4.22 pg/ml vs. 16.57 ± 6.44 pg/ml, t=5.645) of the manipulation group were significantly lower than the control group (P<0.05); the NO (33.15 ± 10.28 μmol/ml vs.34.22 ± 11.05 μmol/ml, t=1.364) of the manipulation group was higher than the control group without significance(P>0.05). Conclusions Manipulation combined with external application of Chinese medicine can reduce the content of joint fluid IL-1β, TNF-α, and the NO after knee joint arthroscope surgery of osteoarthritis, and can improve the function of knee joint, reduce pain, improve the quality of life.