MicroRNA for preventing and treating diabetes mellitus complications:research advances / 国际药学研究杂志

ABSTRACT

Diabetes mellitus is a chronic disease critical to human health. Its complications can lead to some organs and tis?sues damage and are the major cause of death in diabetic patients. As a new type of diagnosis and treatment ,microRNA(miRNA)play an important role in the pathogenesis of diabetes mellitus and its complications. MiRNAs associated with diabetes are becoming an im?portant therapeutic target for diabetic complications. This review summarizes the effects of miRNAs on the pathogenesis of diabetic car?diomyopathy and diabetic nephropathy,and discusses its role in the diagnosis and treatment of diabetes mellitus and its complications.