Risk factors and clinical outcomes of acute kidney injury among subarachnoid hemorrhagic patients / 实用医学杂志

ABSTRACT

Objective To explore the risk factors and clinical outcomes of acute kidney injury(AKI) among subarachnoid hemorrhagic(SAH)patients. Methods We retrospectively reviewed and analyzed the clini-cal data of 269 SAH patients from the neurology ICU between Jan. 2012 and Oct. 2013. Clinical features of AKI and non-AKI patients were compared.Multi-logistic regression was done to find the risk factors concerning with the incidence of AKI. Results A total of 39(14.5%)patients developed AKI.The patients with AKI appeared to be older at age,higher at NIHSS score,lower at GCS score than the non-AKI patients(P<0.05 for all).Moreover, the percentage of proteinuria,infectious complications and diuretics administration were significantly higher in the AKI patients(P<0.05 for all).Multi-logistic regression analysis showed that independent risk factors of AKI were age,GCS score and infectious complication[OR(95% CI)were 1.037(1.006,1.068),0.873(0.802,0.951), 3.624(1.543,8.514),respectively;P < 0.05 for all]. The AKI patients also had a higher hospital mortality rate (28.2%)vs.that in non-AKI(0.8%,P<0.01). Conclusions AKI has a higher incidence among SAH patients and AKI patients tend to have higher hospital mortality rate. Prevention of AKI seems to be very important among these patients.