Association of the gene polymorphism of cytotoxic T lymphocyte-associated antigen-4 with Graves ophthalmopathy in Qinghai Tibetans / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 962-964, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-663841
ABSTRACT
To investigate the association of the gene polymorphism of cytotoxic T lymphocyte-associated antigen-4(CTLA-4)with Graves'ophthalmopathy(GO)in Qinghai Tibetans. 130 case of Graves'disease(GD)were selected from June 2013 to November 2016 in The People's Hospital of Qinghai Province. These patients were assigned into 2 groups,GO(n=71)and GD without GO(n=59). The genotypes and alleles of CTLA-4 gene were detected by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP). Distribution of CTLA-4 exon 1 (+49A/G)genotype frequencies(AA,AG,and GG)was different between 2 groups.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2017
Type:
Article
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