Optimization of Extraction Technology of Ilex Chinensis Sims by Box-Behnken Response Surface Method / 中国药师
China Pharmacist
;
(12): 2149-2152, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-664017
ABSTRACT
Objective:
To optimize the extraction process of Ilex chinensis Sims by Box-Behnken response surface method. Meth-odsThe HPLC determination of pedunculoside was performed and validated. With the extraction rate of pedunculoside as the index, the influencing factors including material-liquid ratio, ethanol concentration, reflowing temperature and decocting frequency were opti-mized by Box-Behnken response surface method.Results:
The optimized parameters were as followsthe material/liquid ratio was 110, the ethanol concentration was 70%, the ultrasonic temperature was 80℃,and the decocting frequency was three times. Conclu-sionThe HPLC method and the best extraction conditions are reliable.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2017
Type:
Article
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