Depressor Substances Test and Histamine Test for the Quality Control of Deproteinized Culf Blood Extrac-tives Injection / 中国药师
China Pharmacist
;
(12): 2264-2266, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-664086
ABSTRACT
Objective:
To explore the applicability of depressor substances test and histamine test for the quality control of depro-teinized culf blood extractives injection.Methods:
Depressor substances test and histamine test were carried out on 10 batches of deproteinized culf blood extractives injection samples.Results:
Some samples showed positive reactions in the experiments. The correl-ative analysis showed positive correlation existed between the results of depressor substances test and histamine test. However, part of samples causing blood pressure decrease in anesthetized cats showed negative or relatively reduced results in histamine test. Conclu-sionDeproteinized culf blood extractives injection may be contaminated by depressor substances. Part of these substances may not be histamine analogue, therefore, depressor substances test may be considered in the quality control of the product.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2017
Type:
Article
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