Survey of distribution and drug resistance of pathogenic bacteria in patients with oral and maxillofacial infections / 国际检验医学杂志

ABSTRACT

Objective To investigate the distribution and drug resistance of pathogens in patients with oral and maxillofacial in-fection.Methods A total of 73 patients with oral and maxillofacial infection in our hospital from January 2012 to December 2016 were selected.The sputum samples were isolated and cultured,and gram positive bacteria susceptibility test was performed by GN201 method.Gram negative bacteria susceptibility test was performed by GP method.Results A total of 71 strains of pathogen-ic bacteria were isolated from 73 cases of diabetic patients with oral and maxillofacial infections..Among them,there were 48 strains of gram negative bacteria,accounting for about 67.61%,21 strains of gram positive bacteria,accounting for 29.58%,and 2 strains of fungi accounting for 2.82%.Among gram negative bacteria Klebsiella pneumoniae was the most,in 19 strains,followed by 17 strains of Pseudomonas aeruginosa,9 strains of Escherichia coli,3 strains of others;among gram positive bacteria,Staphylococcus aureus were the most,in 10 strains,followed by 8 strains of Staphylococcus epidermidis,3 strains of Enterococcus;gram negative bacteria were mainly resistant to ceftazidime,levofloxacin.The resistance rate of Klebsiella pneumoniae to ceftazidime was 94.74%, and the resistance rate to levofloxacin was 68.42%;the resistance rate of Pseudomonas aeruginosa to ceftazidime was 100.00%,and the resistance rate to levofloxacin was 88.24%.The gram positive bacteria were mainly resistant to penicillin G and vancomycin;the resistance rate of Staphylococcus aureus to penicillin G was 90.00%,and the resistance rate to vancomycin was 100.00%;the re-sistance rate of Staphylococcus epidermidis to penicillin G was 87.50%,and the resistance rate to vancomycin was 75.00%.Conclu-sion Oral and maxillofacial infection in diabetic patients are mainly Gram-negative bacteria.The resistance rates of major Gram-negative bacteria were relatively high to ceftazidime and levofloxacin.The resistance rates of major gram positive bacteria to penicil-lin G and vancomycin were relatively high.