Research progress on the role of SIRT in intestinal barrier / 基础医学与临床
Basic & Clinical Medicine
; (12): 103-106, 2018.
Article
in Zh
| WPRIM
| ID: wpr-664988
Responsible library:
WPRO
ABSTRACT
SIRT is a family of highly conserved nicotine adenine dinucleotide ( NAD+)-dependent protein deacetylase which regulates several processes including cell gene stability , metabolism , aging and apoptosis . Studies have shown that SIRT has protective effects on intestinal barrier , which influences the structure and function of intestinal barrier by controlling the release of inflammatory cytokines , regulating the expression of tight junction protein in intestinal epithelial , and changing the number of Paneth and goblet cells in the intestine .
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WPRIM
Language:
Zh
Journal:
Basic & Clinical Medicine
Year:
2018
Type:
Article