A Clinical and Histopathological Study of Cutaneous Squamous Cell Carcinoma / 대한피부과학회지

ABSTRACT

BACKGROUND: The cutaneous squamous cell carcinoma(SCC) is a malignant proliferation of the keratinocyte of the epidermis. It may have the potential to metastasize distally in contrast to the cutaneous basal cell carcinoma (BCC). Our lives were being lengthened gradually and our society was being polluted by many causative factors. Because many kinds of cutaneous malignant tumors occurred to the aged and resulted from the severe pollution, a lot of people have been interested in SCC. OBJECTIVE: In this study we investigated the recent trend of the cutaneous squamous cell carcinoma in clinical and histopathological aspects. METHODS: Seventy one cases of SCC who had visited the Department of Dermatology, Chungnam University Hospital during the last 17 years(between 1983 and 1999) were confirmed in histopatho-logical review. The observation of occurrence rate in years, age and sex distribution, onset, site, cause, histopathological malignancy and treatment was done, retrospectively. RESULTS: 1. The occurrence of the cutaneous squamous cell carcinoma in males was one and half times more than in females(M>F1.63x). Age distribution showed almost above 60 years old(about 74%). 2. The common sites (in decreasing order) were face(56%), extremities(upper>lower), other sites and most etiologic factors were idiopathic(71%), in 2 cases metastatic. 3. Histopathologically, the subtype of SCC was verrucous(7%), acantholytic(10%), spindle cell(6%), and the degree of differentiation was well-, moderate-, poor-differentiated (respectively 25%, 32%, 20%), and SCC invaded to full dermis(84%) and subcutis(9%). 4. Various treatments were done and among them the simple excision(53%) was common. 5. One case recurred and four cases metastasized to adjacent lymph node. One case expired. CONCLUSION: We investigated the recent trend of the cutaneous squamous cell carcinoma through our cases of SCC who had visited the department of dermatology, chungnam university hospital.