Clinical Observation of Intensive Treatment with Antibiotics and Chinese Medicine Fule Tablets for Treatment of Pelvic Inflammatory Disease / 广州中医药大学学报

ABSTRACT

Objective To investigate the short-term clinical effect of intensive treatment with antibiotics and Chinese medicine Fule Tablets for pelvic inflammatory disease (PID). Methods A total of 240 PID patients were randomly divided into observation group and control group,120 cases in each group. The observation group was given oral use of antibiotics (Cefodizime or Cefixime Granules + Ornidazole)for 14 days (d1-d14)and Fule Tablets orally for 30 days(d1-d30). The control group was only given oral use of antibiotics(Cefodizime or Cefixime Granules+Ornidazole)for 14 days (d1-d14). Visual Analogue Scale (VAS)scores for lower abdominal pain, tenderness of the uterus or adnexal region, body temperature, vaginal secretions, and ultrasonogram were observed after treatment for 7, 14 and 30 days in both groups. And the therapeutic effect was also evaluated. Results(1)After treatment,VAS scores for lower abdominal pain,tenderness of the uterus or adnexal region, fever, vaginal secretions, pelvic hydrops, adnexal thickening or adnexal mass in the two groups were much improved after treatment (P < 0.05 compared with those before treatment),and the improvement of VAS scores for lower abdominal pain,tenderness of the uterus or adnexal region,vaginal secretions,and pelvic hydrops in the observation group on day 30 was superior to that in the control group (P < 0.05). (2)After treatment for 7,14 days,the differences of the therapeutic effect between the two groups were insignificant(P>0.05). After treatment for 30 days,the therapeutic effect of the observation group was much stronger than that in the control group (P < 0.05). Conclusion The intensive treatment with antibiotics and Chinese medicine Fule Tablets has stronger effect for the treatment of PID than antibiotics alone, which is effective on relieving clinical symptoms and signs,shortening the course of disease,and reducing or preventing the occurrence of sequelae.