Progress of molecular detection of Schistosoma / 中国血吸虫病防治杂志

ABSTRACT

Schistosomiasis diagnosis plays an important role in the schistosomiasis control. The early detection of schistosomi-asis can help to find the infectious source and prevent advanced schistosomiasis effectively. Up to now,serodiagnosis and parasi-tological diagnosis are used commonly to detect the infection of Schistosoma. As the schistosomiasis control program continues in China,the infection rate and infection intensity of Schistosoma japonicum are decreased significantly,which makes the serodiag-nosis and parasitological diagnosis limited for lacking of sensitivity and timeliness. The molecular diagnosis has been developed greatly because of its timeliness,high specificity and sensitivity,which promotes the development and improvement of schistoso-miasis diagnosis. In the endemic areas where schistosomiasis is limited and the infection rate is low ,the molecular diagnosis pro-vides a potential platform for the early detection and micro detection efficiently. Here,we provide a review that mainly emphasiz-es the progress of molecular detection of schistosomiasis.