Effect of vein pump injection of epinephrine on serum potassium during gastric cancer radical surgery / 实用医学杂志

ABSTRACT

Objective To investigate vein pump injection of epinephrine on the effect of serum potassium during gastric cancer radical surgery. Method Forty patients with ASA grade Ⅱ~Ⅲ underwent surgery within a time limit of gastrointestinal under general anesthesia. All patients were randomly divided into the experimental group and the control group.Patients in the experimental group received continuous intravenous injections of adren-aline[0.03 to 0.1 μg/(kg·min)].Patients in the control group received equal dose of saline.Potassium concentra-tions at different time points were determined and compared between patients in two groups. Results No signifi-cant differences were observed in gender and age distribution of patients in the experimental group and the control group. Compared with the control group,potassium concentration was significantly decreased in patients at T3mo-ment(30 min pump injection of norepinephrine)(P<0.05),but was lower than that of patients in the experimen-tal group at T1moment(before anesthesia)(P<0.05).Compared with the control group,potassium concentration was significantly increased in the experimental group at T4moment(pump adrenaline injection for 10 min)(P <0.05),which was also significantly higher than that in the experimental group at T1moment(P < 0.05). Mean-while,compared with the control group,potassium concentration was also significantly increased in the experimen-tal group at T5moment(stop the pump adrenaline injection for 30 min),which was also significantly higher than that in the experimental group at T1moment(P < 0.05). Conclusions Intravenous injection of adrenaline can reduce potassium concentration in patients received gastrointestinal surgery,and potassium concentration can be increased after adrenalin injection was stopped.