Efficacy of radiofrequency ablation performed under sevoflurane anesthesia in pediatric patients with ventricular premature beats / 中华麻醉学杂志

ABSTRACT

Objective To evaluate the efficacy of radiofrequency ablation performed under sevoflurane anesthesia in the pediatric patients with ventricular premature beats (VPBs).Methods Twenty American Society of Anesthesiologists physical status Ⅰ or Ⅱ pediatric patients,with non-organic heart disease and VPBs,aged 3-12 yr,weighing 19-53 kg,undergoing elective radiofrequency ablation,were divided into propofol group (Pro group) and sevoflurane group (Sev group) using a random number table.Anesthesia was induced with midazolam 0.05 mg/kg,sufentanil 0.3-0.5 μg/kg,propofol 2.5-4.0 mg/kg (in Pro group) and 8％ sevoflurane (in Sev group).Supreme laryngeal mask airway was placed when eyelash reflex disappeared.Propofol 6 mg· kg-1 · h-1 was intravenously infused in Pro group,and 2％-3％ sevoflurane was inhaled in Sev group,and bispectral index value was maintained at 50-60.The frequency of VPBs developed was recorded before induction and at 1,5 and 10 min after induction,and the recurrence was observed within 1 month after operation.Results Compared with that before induction,the frequency of VPBs developed was significantly decreased at 1,5 and 10 min after induction in Pro group (P＜0.05),and no significant change was found in Sev group (P＞0.05).The frequency of VPBs developed was significantly higher at 1,5 and 10 min after induction in Sev group than in Pro group (P＜0.05).The recurrent rate was 30％ within 1 month after operation in Pro group,no recurrence was found in Sev group,and there was significant difference between Sev group and Pro group (P＜0.05).Conclusion The efficacy of radiofrequency ablation performed under sevoflurane anesthesia is better than that performed under propofol anesthesia in the pediatric patients with VPBs.