Progress in treatment of previously untreated oligometastatic nasopharyngeal carcinoma / 中华放射肿瘤学杂志

ABSTRACT

The treatment strategies and prognosis of previously untreated oligometastatic nasopharyngeal carcinoma (NPC) are extremely different due to the heterogeneity of this disease. More and more studies have found the survival advantages of oligometastatic NPC over NPC with multiple metastases. In addition to systemic chemotherapy,the primary tumor and metastatic lesions should be considered in the treatment of previously untreated oligometastatic NPC.Adding radical radiotherapy for primary tumor and aggressive managements for metastatic lesions to the systemic chemotherapy can substantially improve the survival of patients,even achieving a radical cure. Several molecular markers and prognostic models can screen out some patients who will benefit from aggressive treatment,but more studies are needed in the future.