Adverse reactions and symptomatic treatment of immunological checkpoint inhibitors in tumor therapy / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 860-863, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-666238
ABSTRACT
Immunological checkpoint inhibitors include monoclonal antibodies of cytotoxic T lymphocyte antigen-4 (CTLA-4) and programmed cell death-1 (PD-1).Anti-CTLA-4 drug ezetimab (ipilimumab)and anti-PD-1 drug (pembrolizumab and nivolumab) are approved for the treatment of melanoma and non-small cell lung cancer.The effects of these drugs on renal cell carcinoma,bladder cancer,breast cancer,gastrointestinal cancer and other types of cancers are still in large-scale clinical trials.These drugs have good effects in the clinical application,but they inevitably lead to many adverse reactions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2017
Type:
Article
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