The relationship between DNA methylation profile of peripheral blood and smoking / 中国法医学杂志
Chinese Journal of Forensic Medicine
;
(6): 508-511, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-666525
ABSTRACT
Objective To evaluate the potential application of separating smoking individuals from non-smoking ones by DNA methylation profiles from peripheral blood. Methods Human genome-wide DNA methylation data were downloaded from NIH GEOdata base. DNA methylation values from certain CpG sites were used to evaluate their significance between smokers and non-smokers by Student's T Test, as well as the clustering analysis. Results There are significant DNA methylation between smokers and non-smokers for certain CpGs. Conclusion Detection of methylation status from human peripheral blood can distinguish smokers from non-smokers.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Forensic Medicine
Year:
2017
Type:
Article
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