Analysis of physiology and biochemistry indicators of garrison and field training troops at high altitude / 解放军医学杂志

ABSTRACT

Objective To investigate the effects of plateau hypoxia environment on the physiology and biochemistry indicators of troops executing different combat mission.Methods Troops included the soldiers in camp (station altitude 4030m and 4600m) and those soldiers in field training (altitude 4300m) for one month.Blood samples were collected and the physiology and biochemistry indicators were detected including heart rate (HR),blood pressure (BP),oxygen saturation (SpO2) and the concentrations of hemoglobin (Hb),serum total protein (TP),albumin (ALB) and globulin (GLB),the ratio of albumin and globulin (A/G),concentrations of total cholesterol (TC),triglycerides (TG),high-density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C),creatine kinase (CK),lactic dehydrogenase (LDH),aspartate aminotransferase (AST),alanine aminotransferase (ALT) and AST/ALT.Results The HR was significantly higher in soldiers of field training (82.25 ± 14.10 beats/min) than in soldiers stationed in camp (74.18 ± 9.02 beats/min,P＜0.01),while the oxygen saturation was obviously lower in the former (88.25％ ± 2.41％) than in the latter (89.38％ ± 2.44％,P＜0.05).The BP between the two groups showed no significant difference (P＞0.05).The concentration of Hb and the prevalence of plateau polycythemia were significantly higher in soldiers of field training (211.6 ± 17.4g/L and 55.6％) than in soldiers stationed in camp (199.3 ± 22.7g/L and 25.7％,P＜0.001).The concentrations of serum protein were both sufficient in the two groups.The prevalence of dyslipidemia was obviously higher in soldiers of field training (70.5％) than in soldiers stationed in camp (34.0％,P＜0.001),the concentration of HDL-C was significantly lower and the prevalence of low HDL-C blood disease was markedly higher in the former (0.81 ± 0.21nmol/L and 65.9％) than in the latter (1.01 ± 0.27nmol/L and 29.8％,P＜0.001).No significant differences were observed in the concentrations of TC,TG and LDL-C between the two groups (P＞0.05).The concentration of serum LDH was significantly higher and the abnormality rate of LDH was also higher in soldiers of field training (273.70 ± 136.74U/L and 72.7％) than in soldiers stationed in camp (205.19 ± 77.94 U/L and 51.1％,P＜0.01 and P＜0.05).Conclusions The protein nutrition in plateau soldiers is sufficient,but the prevalence of plateau polycythemia,dyslipidemia and the abnormality rate of LDH were higher in soldiers of field training than in soldiers stationed in camp.Regular physical examination should be taken into consideration,early prevention and treatment is also important.