SOX4 gene and lung development / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 689-691,696, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-666830
ABSTRACT
SOX4 is a member of the group C subfamily of the SOX transcription factors and has a criti-cal role during embryogenesis and in controlling cell fate.SOX4 can participate in TGF-β,Wnt signaling ways to mediate cell differentiation,proliferation,migration.SOX4 can facilitate epithelial-mesenchymal transition by di-rectly regulating EZH2 expression.It is one of the 64 genes that constitute a general signature in all human canc-ers.SOX4 is widely expressed in lung and establishes the lung structure in lung development.Here,we provide an overview of role of SOX4 in cell and lung development.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2017
Type:
Article
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