Prenatal MRI assessment of fetal congenital high airway obstruction syndrome / 中华放射学杂志

ABSTRACT

Objective To investigate the manifestation and diagnostic value of the congenital high airway obstruction syndrome(CHAOS)in fetal MRI.Methods Prenatal fetal MRI images were reviewed in 9 fetuses from February 2014 to February 2017 which were screening by ultrasound and underwent MR examination within 2 days. Scanning sequence included HASTE, True-FISP, T2WI、T1WI and DWI sequence. If found suspicious airway obstruction, the fetus will be add the sequence in coronal planes. Prenatal US and MR imaging findings were compared with specimen MR imaging and pathological results. Results All the fetuses viewed demonstrated the following MRI findings:bilateral lung volume increased, increased lung signal on T2WI, dilated airway below the lever of obstruction, flattened or inverted hemidiaphragms,centrally positioned and compressed heart.Ascites and anasarca could be find in 8 cases. Prenatal MRI identified the level of obstruction was 5 cases in laryngeal and 4 cases in tracheal.Four cases of laryngeal obstruction and 3 cases of tracheal obstruction were finally confirmed by autopsy.One case died in intrauterine,and the other 1 case was lost to follow-up.Conclusion MRI shows a special performance in fetals with CHAOS,accurately identifies the level of airway obstruction,and can provide help for perinatal management.