Research on risk factors of neonatal hypoglycemia / 中国医师进修杂志

ABSTRACT

Objective To analyze the risk factors of neonatal hypoglycemia, and provide evidence for prevention of neonatal hypoglycemia. Methods The clinical data of 120 neonates with hypoglycemia (case group) and 120 neonates without hypoglycemia (control group) were retrospectively analyzed. The risk factors of hypoglycemia were analyzed by multivariate Logistic regression analysis. Results The neonates of low birth weight, small gestational age, premature, pregnant woman with gestational diabetes mellitus,neonatal asphyxia and erythrocytosis in case group were significantly more than those in control group(35 cases vs.13 cases,21 cases vs.6 cases,31 cases vs.11 cases,13 cases vs. 4 cases,27 cases vs.15 cases and 15 cases vs.3 cases),and there were statistical differences(P<0.01 or<0.05).The multivariate Logistic regression analysis result showed that premature,low birth weights, small gestational age, pregnant woman with gestational diabetes mellitus, neonatal asphyxia and erythrocytosis were the risk factors of neonatal hypoglycemia(OR=3.451,3.389,4.030,3.523,2.032 and 5.571;95% CI 1.642-7.253,1.687-6.807,1.564-10.384,1.114-11.139,1.019-4.052 and 1.569 - 19.785; P<0.01 or <0.05). Conclusions The premature, low birth weights, small for gestational age,pregnant woman with gestational diabetes mellitus,neonatal asphyxia and erythrocytosis are the risk factors of neonatal hypoglycemia. Newborns with hypoglycemia risk factors should be regularly tested for blood glucose,and doctors should take immediate actions to correct hypoglycemia in order to avoid hypoglycemia brain damage.