Prognosis Affects of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio of Peripheral Blood for Patients with Acute Lung Infarction / 现代检验医学杂志

ABSTRACT

Objective To described the prognosis affects of blood neutrophil to lymphocyte and platelet to lymphocyte for acute plumonary embolism patients.Methods Collected 164 acute plumonary embolism patients from 2010 to 2015,and they were divided into survivor group (n=136) and death group (n=28).And collected the data for basic clinical pathological and biochemical characteristics,to assess the correlation.Results The study found that the mortality of 164 cases of APE patients was 17.07％ (28/164).Multivariate Logstic regression analysis found that the lower systolic blood pressure (OR=0.923,95％ CI0.872～0.991,P=0.016) and the wells score (OR=1.138,95％ CI1.002～1.478,P=0.036),higher pulmonary artery systolic pressure (OR=1.090,95 ％ CI1.031 ～ 1.316,P =0.014),NLR (OR =1.132,95 ％ CI1.040 ～1.238,P=0.012),PLR (OR=1.002,95％ CI1.000～1.009,P=0.010),brain natriuretic peptide (OR=1.002,95％ CI1.000～1.007,P=0.017),PESI score (OR=1.100,95％ CI1.032～1.200,P=0.012) were the significant independent risk factors of death for patients with APE,NLR and PLR had significant correlation with other significant independent risk factors.Kaplan-Meier curve analysis found that the overall survival of APE patients with NLR≤5.64,PLR≤184 were significantly higher than APE patients with NLR＞5.64,PLR＞184 (P=0.01),respectively.Conclusion NLR and PLR could be used as independent prognostic factors in patients with acute pulmonary embolism,and the risk of death was higher in patients with higher level NLR or PLR.