Research progress on genetic etiology of keratoconus / 眼科新进展
Recent Advances in Ophthalmology
;
(6): 1083-1087, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-667524
ABSTRACT
Keratoconus (KC) is a common cornea ectatic disorder characterized by myopia,irregular astigmatism and other visual impairment caused by corneal thinning and cone-shaped protrusion.With a wide range of effects,the etiology of this disease is unknown,and genetic factors may be involved in its pathogenesis.This paper summarizes the research progress on KC genetic etiology for reviewing the selected candidate genes and loci based on traditional/genome-wide linkage studies,genome-wide association studies and central corneal thickness in recent years.Genetic studies on KC pathogenesis will advance our understanding of this disease and further promote the development of potential therapies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Recent Advances in Ophthalmology
Year:
2017
Type:
Article
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