Yupingfeng powder combined with conventional western medicine therapy for patients with chronic bronchitis acute clinical studies / 国际中医中药杂志

ABSTRACT

Objective To evaluate the effect of Yupingfeng powder for the patients with chronic bronchitis acute episodes. Method A total of 80 patients with chronic bronchitis acute phase were divided into two groups, 40 in each group, using the random number table method. The control group were treated with conventional western medicine therapy, and the treatment group were treated with Yupingfeng powder on the intervention of control group.Two groups were treated 2 weeks. The pulmonary function before and after treatment, the changes in inflammatory cytokines, and TCM syndrome scores, and clinical effect rates were detected and compared. Results The observation group total effective rate was 92.5% (37/40), and the control group was 72.5% (29/40). The difference was statistically significant (χ2=5.541, P=5.541). After treatment, the TCM syndrome scores(4.58 ± 1.16 vs.7.74 ± 2.35,t=3.256)in the observation group was significantly lower than that in the control group(P<0.05).The FVC(2.58 ± 0.35 L vs.2.15 ± 0.32 L,t=5.664),TLC(2.68 ± 0.49 L vs.2.41 ± 0.37 L,t=3.523),VC(2.43 ± 0.38 L vs.1.52 ± 0.35 L,t=11.152),MVV(72.5 ± 14.54 L vs.51.2 ± 12.47 L, t=7.305) in the observation group were significantly higher than those in the control group (Ps<0.01). The hs-CRP serum(12.55 ±4.55 mg/L vs.24.72 ± 5.70 mg/L,t=3.543),the WBC[(5.03 ± 1.10)×109/L vs.(7.52 ± 1.41)×109/L,t=2.347)],percentage of neutrophils(60.32% ± 4.49 % vs.71.13% ± 4.14%,t=3.651)levels in the observation group were significantly lower than those in the control group (P<0.01). Conclusions The Yupingfeng powder combined with conventional western medicine therapy can improve lung function in patients with chronic bronchitis acute, lower the levels of inflammatory cytokines, and improve the clinical effect.