A clinical experience of endoscopic treatment for benign and malignant tumors of skull base / 天津医药

ABSTRACT

Objective To summarize the surgical skills and experience of skull base surgery by endoscopic treatment. Methods A total of 8 cases with benign and malignant tumors were treated in our hospital from August 2014 to December 2016, including orbital region, sellar region, clivus, pterygopalatine fossa and infratemporal fossa. The endoscopic endonasal surgery involved optic nerve decompression, internal carotid artery, treatment of middle skull base and clivus dura tumors, opening of pterygopalatine fossa and infratemporal fossa. The anti infection and anti inflammation treatment of the dura and the internal carotid artery and the treatment of the complications such as diplopia, vision decrease, and the adjustment of pituitary hormones were given to patients after operation. Results The visual of a patient with fungal sinusitis recovered from no light perception to "finger/1 m" at one week after surgery. One of the patients with pituitary tumor underwent unilateral eyeball abduction limitation. The symptoms disappeared after one week treatment. Insipidus occurred in 1 patient with invasive pituitary adenoma, after symptomatic treatment for half a month, urine volume and specific gravity tend to normal. Two patients with adenoid cystic carcinoma underwent enhanced MRI examination at 10 days, 3 months and 1 year after operation, both achieved total resection and no local recurrence. The patient with nasopharyngeal carcinoma reached total resection after operation, and showed no local recurrence after six-month follow-up. All the 8 patients achieved complete resection in one stage, without any serious complication after operation. Conclusion Endoscopic endonasal surgery is an important method for the treatment of tumour in anterior skull base, which needs extensive surgical experience and cooperation with other clinical departments.