Update in the etiology and treatment of sexual precocity / 소아과
Korean Journal of Pediatrics
; : 718-725, 2006.
Article
in Ko
| WPRIM
| ID: wpr-66799
Responsible library:
WPRO
ABSTRACT
The pubertal activation of gonadotrophin releasing hormone(GnRH) requires coordinated changes in excitatory or inhibitory amino acids, growth factors, and a group of transcriptional regulators. The age of onset of puberty is progressing to younger age. Factors affecting early puberty include genetic traits, nutrition(body fat) and exposure to endocrine disrupting chemicals. In rapidly progressing central precocious puberty, gonadotrophin releasing hormone(GnRH) agonists(GnRHa) appear to increase final height if treated early stage. Further large scaled long-term follow-up study of the effects of GnRHa on final height is needed.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Puberty, Precocious
/
Puberty
/
Age of Onset
/
Intercellular Signaling Peptides and Proteins
/
Endocrine Disruptors
/
Amino Acids
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
Limits:
Adolescent
/
Humans
Language:
Ko
Journal:
Korean Journal of Pediatrics
Year:
2006
Type:
Article