Analysis of Risk Factors for Parapneumonic Pleural Effusion in Patients with Community Acquired Pneumonia in the Emergency Department / 中国医科大学学报

ABSTRACT

Objective To evaluate the risk factors for parapneumonic plettral effusion (PPE) in patients with community acquired pnetrmonia (CAP) in the emergency department.Methods A total of 276 patients with CAP were enrolled.Based on the presence of PPE,they were divided into a PPE group and a non-PPE (NPPE) group.Age,gender,vital signs,initial laboratory results,length of stay,28-day mortality,and CURB-65 score were collected.A univariate analysis was performed,and logistic regression analysis was used to determine statistical significance.Results There were 46 patients in the PPE group and 230 in the NPPE group.The univariate analysis indicated that differences in age,gender,white blood cell count,platelet count,and serum alanine aminotransferase were not statistically significant (P ＞ 0.05) between the two groups.The differences in hyponatremia,hypoproteinemia,serum procalcitonin levels,and CURB-65 scores were statistically significant (P ＜ 0.05).The logistic regression analysis revealed that hyponatremia,hypoproteinemia,and serum procalcitonin level were independent risk factors.The patients in the PPE group were more likely to be admitted (22.1％ vs 7.5％,P ＜ 0.05) and had longer hospital stays (median 16 days vs 5 days,P ＜ 0.05) than those in the NPPE group.However,there was no difference in 28-day mortality between PPE and NPPE groups (8.6％ vs 8.3％,P ＞ 0.05).Conclusion CAP patients with PPE in the emergency department were more likely to be admitted and had longer hospital stays,Hyponatremia,hypoproteinemia,and serum procalcitonin were independent risk factors for pleural effusion.Therefore,to decrease morbidity,as well as economic burden,we should pay more attention and provide earlier treatment to patients with PPE.