Scientific assessment of post-exercise oxidative stress and reasonable antioxidant supplement / 中国组织工程研究

ABSTRACT

BACKGROUND:The accumulation of free radicals after high-intensity exercise is an important factor for exercise induced fatigue and injuries,while the intake of exogenous antioxidants can improve the body function and antioxidant ability.There is still a lack of effective guidance and research on the reasonable supplement of antioxidants during and after exercise.OBJECTIVE:To analyze the scientific methods for assessing post-exercise oxidative stress and the effectiveness of antioxidant supplement during exercise.METHODS:The ScienceDirect database was retrieved for relevant articles using the keywords of "sports,oxidative stress,antioxidants,mitochondria".The included literatures addressing post-exercise oxidative stress injury and the antioxidant supplement were analyzed.RESULTS AND CONCLUSION:Exercise can enhance the antioxidant capacity,while a potential risk of oxidative damage will be increased gradually.Reasonable antioxidant supplementation plays an important role in improving the antioxidant ability,delaying the oxidative stress,and relieving damage to cellular structures and functions due to the imbalance between oxidative stress and antioxidant defense system.Supplementary pattern,total amount and timing are the key factors for treatment of oxidative stress damage as well as the adaptive changes of exercise capacity after high-intensity exercise.The variations of biomarkers such as 8-OHdG in human body fluid can be used as an important reference index for evaluating post-exercise oxidative stress,exercise adaptive recovery state and antioxidant supplementation.