Optimization of Alcohol Extraction Process of Yiqigutuo Granules by Orthogonal Test / 中国药师
China Pharmacist
;
(12): 410-413, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-669684
ABSTRACT
Objective:
To optimize the alcohol extraction process of Yiqigutuo granules.Methods:
Using the L9 (34 ) orthogonal design method, the active ingredients astragaloside and ferulic acid in the formula were quantitatively analyzed by HPLC. The concen-tration and amount of ethanol, extraction times and extraction duration and the other parameters affecting the extraction volume were ex-amined.Results:
Analysis of variance showed that the ethanol concentration and extraction times had significant influence on the ex-tract content and the extraction of ferulic acid. The best alcohol extraction process was as follows70% ethanol of 10-fold volume, ex-tracting 3 times with 1. 5h for each time.Conclusion:
The process is stable, and suitable for the industrial production.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2015
Type:
Article
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