Study on Quality Standard for Chidan Ganxian Granules / 中国药师
China Pharmacist
;
(12): 1027-1030, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-669863
ABSTRACT
Objective:
To establish the quality standard for Chidan Ganxian granules.Methods:
TLC was used to identify Paeoni-ae Radix Rubra, Rhizoma Polygoni Cuspidati, Radix Salviae Miltiorrhizae, Herba Saururi and Radix et Rhizoma Rhei in Chidan Ganx-ian granules, and the content of paeoniflorin was determined by HPLC. The stationary phase was an Apollo C18 column ( 150 mm × 4. 6 mm, 5 μm), the mobile phase was acetonitrile-water(12. 5∶87. 5), the flow rate was 1. 0 ml·min-1, the detection wavelength was at 230 nm, and the temperature was 30℃.Results:
The characteristic spots of the granules were the same as those of the standard samples without any interference from the negative control. Paeoniflorin had a good linear relationship within the range of 0. 120-1. 436 μg(r=0. 999 4), and the average recovery was 99. 8% with RSD of 1. 80%(n=6).Conclusion:
The method is simple, ac-curate, reliable and reproducible, which can be used in the quality control of Chidan Ganxian granules.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
China Pharmacist
Year:
2015
Type:
Article
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