Optimization of Water Extraction Process for Jinyin Lidan Oral Liquids by Orthogonal Experiment / 中国药师

ABSTRACT

Objective:To investigate the optimal water extraction process of Jinyin Lidan oral liquids. Methods:An orthogonal de-sign was used in the extraction optimization using the yield and content of chlorogenic acid,narigin and neohesperidin as the evaluation indices and the volume of water,extraction times,extraction time and soaking time as the influencing factors. The contents of chloro-genic acid,narigin and neohesperidin were detected by HPLC to screen the best extraction technology. Results:The best water extrac-tion conditions were as followsthe amount of the added water was 8 times of the medicinal materials,the soaking time was 1 h,and the decoction was carried out twice with the duration of 1. 5 h for each. Conclusion:The process is stable and reasonable,which pro-vides research foundation for the production and quality control.