Intracoronary Ergonovine Provocation Test in Patients with Coronary Artery Spasm
Korean Circulation Journal
;
: 53-59, 1994.
Article
in Korean
| WPRIM
| ID: wpr-67006
ABSTRACT
BACKGROUND:
Intravenous ergonovine and intracoronary acetylcholine tests have been used to induce coronary artery spasm, however, potential preblems with each test require a safer and more specific test.METHODS:
To evaluate the usefulness of the intracoronary ergonovine provocation test in patients with coronary artery spasm, this test was performed in 83 patients(male 47, female 36) with normal or near-normal looking coronary angiography or insignificant lesion less than 50% in diameter after routine diagnostic coronary angiography. Ten micrograms of ergonovine maleate diluted in 1 ml of saline was injected into right coronary artery up to 2 times and into left coronary artery up to 3 times. Induction of coronary arterial narrowing more than 75% of luminal diameter with typical chest pain and/or ECG changes in two or more adjacent leads was considered as a positive test.RESULTS:
Intracoronary ergonovine provocation tests were positive in 33 patients among 83 patients. In 24 patients, coronary artery spasm was induced in RCA, 12 patients in LAD and 8 patients in LCX. Coronary artery spasm of 2 sites was observed in 11 patients. In 27 patients, typical chest pain was developed with spasm. The ECG changes during spasm were ST elevation in 19 patients, ST depression in 3 patients, T wave change only in 2 patients and no change in 9 patients. The provocation tests showed focal spasm in 23 patients(70%) and diffuse spasm in 10 patients(30%).CONCLUSION:
Intracoronary ergonovine provocation test appears to be a safe and effective method to provoke the coronary artery spasm.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenobarbital
/
Spasm
/
Chest Pain
/
Acetylcholine
/
Coronary Angiography
/
Coronary Vessels
/
Depression
/
Electrocardiography
/
Ergonovine
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Circulation Journal
Year:
1994
Type:
Article
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