Effect of Amlodipine Atorvastatin Tablets on Blood Pressure and Blood Lipid of Patients with Hypertension Complicated with Coronary Heart Disease / 中国药师

ABSTRACT

Objective:To investigate the effect of amlodipine atorvastatin on blood pressure and blood lipid in the patients with hy-pertension complicated with coronary heart disease (CHD). Methods: Totally 80 cases of outpatients with hypertension complicated with CHD were randomly divided into the observation group (40 cases) and the control group (40 cases). The control group was given amlodipine 10 mg,po,qn, and the observation group was given amlodipine and atorvastatin tablets 20 mg,po,gn, and the treatment course was 6 weeks. The changes of blood pressure and blood lipid in the two groups before and after the treatment were observed, and the clinical curative effect and adverse reactions were also studied. Results:Compared with those before the treatment, systolic blood pressure, diastolic blood pressure and blood fat in the two groups were all improved after the treatment, and the difference was statisti-cally significant (P0. 05). Conclusion: Amlo-dipine atorvastatin tablets can significantly improve blood pressure and blood lipid in the patients with hypertension complicated with CHD with promising clinical curative effect and few side effects, which is worthy of wide use in clinics.