Effects of NS-398 on vascular endothelial growth factor expression in human tongue squamous cell carcinoma Tca8113 cell line / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6)2000.
Article
in Chinese
| WPRIM
| ID: wpr-670866
ABSTRACT
Objective:
To study the effects of NS-398 on the expression of vascular endothelial growth factor (VEGF) in human tongue squamous cell carcinoma Tca8113 cells.Methods:
Tca 8113 cells were exposed to the COX-2 inhibitor NS-398 at 150 ?mol/L for 48,72 and 96 h respectively,then cells were collected. VEGF expression was examined by RT-PCR and Western blot.Results:
NS-398 inhibited VEGF mRNA and protein expression time-dependently in Tca8113 cells.Conclusion:
NS-398 may inhibit VEGF expression in tongue squamous cell carcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Practical Stomatology
Year:
2000
Type:
Article
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